16
Apr
13

Whole brain cellular-level activity mapping in one second


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Medical Anatomy

See on Scoop.itAnatomy

Neuroscientists at Howard Hughes Medical Institute have mapped the activity of nearly all the neurons in a vertebrate brain at cellular resolution, with signficant implications for neuroscience research and projects like the proposed Brain Activity Map (BAM).

Fast volumetric imaging of the larval zebrafish brain with light-sheet microscopy (credit: Misha B Ahrens, Philipp J Keller/Nature Methods)

The researchers used high-speed light sheet microscopy to image the activity of 80% of the neurons in the brain (which is composed of ~100,000 neurons) of a fish larva at 0.8 Hz (an image every 1.3 seconds), with single-cell resolution.

This represents the first technology that achieves whole brain imaging of a vertebrate brain at cellular resolution with speeds that approximate neural activity patterns and behavior, as Nature Methodsmethagora blog noted.

The authors saw correlated activity patterns at the cellular level that spanned large areas of the brain — pointing to the existence of broadly…

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Dr Dubois

SwissChiropractic Clinique

SwissChiropractic Clinique

Dr Dubois, DC, CCSP Dr. Dubois, a Swiss physician, and a Triangle Certified Sport Chiropractor has over 20 years of experience in the treatment and prevention of disorders of the musculoskeletal system. Amongst his patients, two world champions in martial arts (gold medalists in 2005 WMJA), one carrier of the Olympic flame in 2004, and numerous soccer players, swimmers and athletes of all levels who benefited from his chiropractic care.

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